Atomistry » Iron » PDB 8ji3-8k6k » 8jnp
Atomistry »
  Iron »
    PDB 8ji3-8k6k »
      8jnp »

Iron in PDB 8jnp: Crystal Structure of Cytochrome P450 Cfta From Streptomyces Torulosus Nrrl B-3889, in Complex with the Substrate Ikarugamycin

Protein crystallography data

The structure of Crystal Structure of Cytochrome P450 Cfta From Streptomyces Torulosus Nrrl B-3889, in Complex with the Substrate Ikarugamycin, PDB code: 8jnp was solved by P.Jiang, L.P.Zhang, C.S.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.06 / 2.00
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 67.197, 68.383, 108.795, 90, 90, 90
R / Rfree (%) 18.8 / 23.7

Iron Binding Sites:

The binding sites of Iron atom in the Crystal Structure of Cytochrome P450 Cfta From Streptomyces Torulosus Nrrl B-3889, in Complex with the Substrate Ikarugamycin (pdb code 8jnp). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Cytochrome P450 Cfta From Streptomyces Torulosus Nrrl B-3889, in Complex with the Substrate Ikarugamycin, PDB code: 8jnp:

Iron binding site 1 out of 1 in 8jnp

Go back to Iron Binding Sites List in 8jnp
Iron binding site 1 out of 1 in the Crystal Structure of Cytochrome P450 Cfta From Streptomyces Torulosus Nrrl B-3889, in Complex with the Substrate Ikarugamycin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Cytochrome P450 Cfta From Streptomyces Torulosus Nrrl B-3889, in Complex with the Substrate Ikarugamycin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe402

b:20.7
occ:1.00
FE A:HEM402 0.0 20.7 1.0
NC A:HEM402 2.0 22.9 1.0
NB A:HEM402 2.0 19.9 1.0
NA A:HEM402 2.1 19.3 1.0
ND A:HEM402 2.1 20.2 1.0
SG A:CYS345 2.3 19.2 1.0
C1C A:HEM402 3.0 20.5 1.0
C4B A:HEM402 3.0 18.5 1.0
C4C A:HEM402 3.0 25.2 1.0
HB2 A:CYS345 3.0 22.4 1.0
C4A A:HEM402 3.1 21.6 1.0
C1D A:HEM402 3.1 17.3 1.0
C1B A:HEM402 3.1 17.2 1.0
C4D A:HEM402 3.1 19.1 1.0
C1A A:HEM402 3.1 20.1 1.0
H14A A:EIA401 3.1 30.6 1.0
CB A:CYS345 3.3 18.7 1.0
CHC A:HEM402 3.4 21.4 1.0
H13B A:EIA401 3.4 32.3 1.0
CHB A:HEM402 3.4 17.0 1.0
CHD A:HEM402 3.4 26.8 1.0
CHA A:HEM402 3.5 21.1 1.0
H13A A:EIA401 3.5 32.3 1.0
HA A:CYS345 3.7 25.0 1.0
C13 A:EIA401 3.8 26.9 1.0
H A:GLY347 3.9 27.6 1.0
C14 A:EIA401 3.9 25.5 1.0
HB3 A:CYS345 4.0 22.4 1.0
CA A:CYS345 4.1 20.9 1.0
HD1 A:PHE338 4.1 23.9 1.0
C3C A:HEM402 4.2 17.2 1.0
C2C A:HEM402 4.2 21.0 1.0
C3B A:HEM402 4.3 19.5 1.0
C3A A:HEM402 4.3 18.3 1.0
C2A A:HEM402 4.3 18.8 1.0
C2B A:HEM402 4.3 16.6 1.0
C2D A:HEM402 4.3 18.9 1.0
C3D A:HEM402 4.3 21.3 1.0
HHC A:HEM402 4.3 25.7 1.0
HHD A:HEM402 4.4 32.2 1.0
HHB A:HEM402 4.4 20.4 1.0
HHA A:HEM402 4.4 25.3 1.0
H15B A:EIA401 4.6 38.3 1.0
HA3 A:GLY347 4.6 25.1 1.0
H14C A:EIA401 4.6 30.6 1.0
H14B A:EIA401 4.6 30.6 1.0
H A:VAL346 4.6 28.5 1.0
HB1 A:ALA233 4.7 31.9 1.0
N A:GLY347 4.7 23.0 1.0
C A:CYS345 4.7 19.5 1.0
N A:VAL346 4.9 23.7 1.0
CD1 A:PHE338 4.9 19.9 1.0
HE1 A:PHE338 5.0 24.9 1.0

Reference:

P.Jiang, H.Jin, G.Zhang, W.Zhang, W.Liu, Y.Zhu, C.Zhang, L.Zhang. A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450S By Structural Comparison of Ikad and Cfta Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl. 10728 2023.
ISSN: ESSN 1521-3773
PubMed: 37917570
DOI: 10.1002/ANIE.202310728
Page generated: Sat Aug 10 07:19:31 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy