Iron in PDB 8kc9: Human Collagen Prolyl Processing Enzyme Complex, P3H1/Crtap/Ppib Heterotrimer, Bound to Cyclosporin A

All present enzymatic activity of Human Collagen Prolyl Processing Enzyme Complex, P3H1/Crtap/Ppib Heterotrimer, Bound to Cyclosporin A:
1.14.11.7; 5.2.1.8;

The binding sites of Iron atom in the Human Collagen Prolyl Processing Enzyme Complex, P3H1/Crtap/Ppib Heterotrimer, Bound to Cyclosporin A (pdb code 8kc9). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Human Collagen Prolyl Processing Enzyme Complex, P3H1/Crtap/Ppib Heterotrimer, Bound to Cyclosporin A, PDB code: 8kc9:

Iron binding site 1 out of 1 in the Human Collagen Prolyl Processing Enzyme Complex, P3H1/Crtap/Ppib Heterotrimer, Bound to Cyclosporin A


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Collagen Prolyl Processing Enzyme Complex, P3H1/Crtap/Ppib Heterotrimer, Bound to Cyclosporin A within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:234.4 occ:1.00 NE2 A:HIS659 2.2 229.7 1.0 OD1 A:ASP589 2.8 237.6 1.0 CE1 A:HIS659 2.9 229.7 1.0 NE2 A:HIS587 3.1 245.8 1.0 CD2 A:HIS659 3.3 229.7 1.0 CE1 A:HIS587 3.6 245.8 1.0 CG A:ASP589 3.7 237.6 1.0 OD2 A:ASP589 3.9 237.6 1.0 ND1 A:HIS659 4.1 229.7 1.0 CD2 A:HIS587 4.2 245.8 1.0 CG A:HIS659 4.3 229.7 1.0 CZ2 A:TRP675 4.5 198.9 1.0 ND1 A:HIS587 4.7 245.8 1.0

W.Li, J.Peng, D.Yao, B.Rao, Y.Xia, Q.Wang, S.Li, M.Cao, Y.Shen, P.Ma, R.Liao, A.Qin, J.Zhao, Y.Cao. The Structural Basis For the Collagen Processing By Human P3H1/Crtap/Ppib Ternary Complex. Nat Commun V. 15 7844 2024.
ISSN: ESSN 2041-1723
PubMed: 39245686
DOI: 10.1038/S41467-024-52321-6