Iron in PDB 8rme: Structure of the Core Isc Complex Under Turnover Conditions (Frataxin- Bound)

All present enzymatic activity of Structure of the Core Isc Complex Under Turnover Conditions (Frataxin- Bound):
2.8.1.7;

The binding sites of Iron atom in the Structure of the Core Isc Complex Under Turnover Conditions (Frataxin- Bound) (pdb code 8rme). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of the Core Isc Complex Under Turnover Conditions (Frataxin- Bound), PDB code: 8rme:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Structure of the Core Isc Complex Under Turnover Conditions (Frataxin- Bound)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of the Core Isc Complex Under Turnover Conditions (Frataxin- Bound) within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe201 b:132.3 occ:1.00 OD1 D:ASP71 2.1 74.3 1.0 OD2 D:ASP71 2.1 71.4 1.0 SG D:CYS95 2.3 80.0 1.0 SG A:CYS381 2.3 102.8 1.0 CG D:ASP71 2.4 72.7 1.0 CB D:CYS95 3.2 63.5 1.0 N D:CYS95 3.8 64.9 1.0 CB D:ASP71 3.9 66.8 1.0 CB A:CYS381 4.0 101.7 1.0 O D:HOH303 4.1 62.9 1.0 CA D:CYS95 4.2 61.2 1.0 OE2 A:GLU362 4.5 67.9 1.0 O D:GLY70 4.6 81.7 1.0 SG D:CYS138 4.6 79.7 1.0 NZ D:LYS135 4.6 79.0 1.0 C D:GLY70 4.7 76.8 1.0 O D:HOH304 4.7 83.9 1.0 N D:ASP71 4.8 63.5 1.0 CA D:ASP71 4.8 62.5 1.0 C D:GLY94 4.8 48.9 1.0 CA D:GLY94 5.0 45.7 1.0 CD A:GLU362 5.0 67.5 1.0

Iron binding site 2 out of 2 in the Structure of the Core Isc Complex Under Turnover Conditions (Frataxin- Bound)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Structure of the Core Isc Complex Under Turnover Conditions (Frataxin- Bound) within 5.0Å range: probe atom residue distance (Å) B Occ H:Fe201 b:108.9 occ:1.00 OD2 H:ASP71 2.2 70.6 1.0 OD1 H:ASP71 2.3 72.1 1.0 SG E:CYS381 2.3 94.3 1.0 SG H:CYS95 2.3 67.2 1.0 NE2 H:HIS137 2.5 86.1 1.0 CG H:ASP71 2.5 71.6 1.0 CE1 H:HIS137 3.4 86.0 1.0 CD2 H:HIS137 3.4 86.3 1.0 CB H:CYS95 3.6 54.7 1.0 SG H:CYS69 3.7 95.5 1.0 CB E:CYS381 3.9 87.2 1.0 CB H:ASP71 3.9 68.0 1.0 N H:CYS95 4.0 56.9 1.0 SG H:CYS138 4.1 84.1 1.0 CA H:CYS95 4.4 54.3 1.0 ND1 H:HIS137 4.6 86.5 1.0 NZ H:LYS135 4.6 88.1 1.0 CG H:HIS137 4.6 86.8 1.0 CB H:CYS69 4.8 93.5 1.0 CB H:ALA98 4.9 53.3 1.0 CA H:ASP71 4.9 67.8 1.0 CA E:CYS381 5.0 88.2 1.0 N H:ASP71 5.0 70.9 1.0

R.Steinhilper, L.Boss, S.A.Freibert, V.Schulz, N.Krapoth, S.Kaltwasser, R.Lill, B.J.Murphy. Two-Stage Binding of Mitochondrial Ferredoxin-2 to the Core Iron-Sulfur Cluster Assembly Complex. Nat Commun V. 15 10559 2024.
ISSN: ESSN 2041-1723
PubMed: 39632806
DOI: 10.1038/S41467-024-54585-4