Iron in PDB 9cwt: Human Kidney Respiratory Complex I

All present enzymatic activity of Human Kidney Respiratory Complex I:
7.1.1.2;

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 28;

Binding sites:

The binding sites of Iron atom in the Human Kidney Respiratory Complex I (pdb code 9cwt). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 28 binding sites of Iron where determined in the Human Kidney Respiratory Complex I, PDB code: 9cwt:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe501 b:37.0 occ:1.00 FE1 A:SF4501 0.0 37.0 1.0 SG A:CYS382 2.3 23.4 1.0 S2 A:SF4501 2.3 37.0 1.0 S4 A:SF4501 2.3 37.0 1.0 S3 A:SF4501 2.3 37.0 1.0 FE3 A:SF4501 2.7 37.0 1.0 FE4 A:SF4501 2.7 37.0 1.0 FE2 A:SF4501 2.7 37.0 1.0 OG1 A:THR423 3.2 28.0 1.0 CB A:CYS425 3.6 33.2 1.0 CG2 A:ILE424 3.6 26.0 1.0 N A:CYS425 3.7 33.2 1.0 CB A:CYS385 3.8 30.1 1.0 CB A:CYS382 3.9 23.4 1.0 S1 A:SF4501 3.9 37.0 1.0 CA A:CYS425 4.2 33.2 1.0 N A:ILE424 4.4 26.0 1.0 N A:CYS382 4.4 23.4 1.0 CB A:THR423 4.4 28.0 1.0 SG A:CYS385 4.4 30.1 1.0 SG A:CYS379 4.6 32.7 1.0 O A:CYS425 4.7 33.2 1.0 CG A:GLN381 4.7 27.9 1.0 CA A:CYS382 4.7 23.4 1.0 SG A:CYS425 4.8 33.2 1.0 C A:ILE424 4.8 26.0 1.0 C A:CYS425 4.8 33.2 1.0 CB A:ILE424 4.8 26.0 1.0 O A:CYS382 4.9 23.4 1.0 CA A:ILE424 4.9 26.0 1.0

Iron binding site 2 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe501 b:37.0 occ:1.00 FE2 A:SF4501 0.0 37.0 1.0 CB A:CYS425 2.0 33.2 1.0 S4 A:SF4501 2.3 37.0 1.0 S1 A:SF4501 2.3 37.0 1.0 S3 A:SF4501 2.3 37.0 1.0 SG A:CYS425 2.3 33.2 1.0 FE3 A:SF4501 2.7 37.0 1.0 FE4 A:SF4501 2.7 37.0 1.0 FE1 A:SF4501 2.7 37.0 1.0 CA A:CYS425 3.3 33.2 1.0 C A:CYS425 3.9 33.2 1.0 CB A:LEU427 3.9 36.2 1.0 N A:CYS425 3.9 33.2 1.0 S2 A:SF4501 3.9 37.0 1.0 CD1 A:ILE205 4.0 40.6 1.0 CG A:PRO223 4.1 33.6 1.0 N A:LEU427 4.2 36.2 1.0 O A:CYS425 4.3 33.2 1.0 OG1 A:THR423 4.4 28.0 1.0 N A:ALA426 4.4 35.2 1.0 CD A:PRO223 4.6 33.6 1.0 CA A:LEU427 4.6 36.2 1.0 SG A:CYS379 4.6 32.7 1.0 N A:GLY428 4.8 42.3 1.0 CG1 A:ILE205 4.9 40.6 1.0 CG A:LEU427 4.9 36.2 1.0 SG A:CYS385 4.9 30.1 1.0 CB A:PRO223 4.9 33.6 1.0

Iron binding site 3 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe501 b:37.0 occ:1.00 FE3 A:SF4501 0.0 37.0 1.0 SG A:CYS385 2.3 30.1 1.0 S2 A:SF4501 2.3 37.0 1.0 S4 A:SF4501 2.3 37.0 1.0 S1 A:SF4501 2.3 37.0 1.0 FE1 A:SF4501 2.7 37.0 1.0 FE2 A:SF4501 2.7 37.0 1.0 FE4 A:SF4501 2.7 37.0 1.0 CB A:CYS385 2.8 30.1 1.0 OG A:SER378 3.3 36.3 1.0 S3 A:SF4501 3.9 37.0 1.0 CD2 A:LEU427 3.9 36.2 1.0 SG A:CYS382 4.3 23.4 1.0 CB A:LEU427 4.3 36.2 1.0 CA A:CYS385 4.3 30.1 1.0 N A:GLY428 4.5 42.3 1.0 CB A:SER378 4.5 36.3 1.0 CB A:CYS425 4.5 33.2 1.0 N A:GLY380 4.5 27.0 1.0 OG1 A:THR423 4.6 28.0 1.0 CG A:LEU427 4.7 36.2 1.0 N A:CYS379 4.7 32.7 1.0 SG A:CYS425 4.7 33.2 1.0 C A:CYS385 4.9 30.1 1.0 SG A:CYS379 4.9 32.7 1.0 C A:LEU427 5.0 36.2 1.0

Iron binding site 4 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe501 b:37.0 occ:1.00 FE4 A:SF4501 0.0 37.0 1.0 SG A:CYS379 2.3 32.7 1.0 S3 A:SF4501 2.3 37.0 1.0 S2 A:SF4501 2.3 37.0 1.0 S1 A:SF4501 2.3 37.0 1.0 FE1 A:SF4501 2.7 37.0 1.0 FE3 A:SF4501 2.7 37.0 1.0 FE2 A:SF4501 2.7 37.0 1.0 N A:GLY380 3.1 27.0 1.0 CB A:CYS379 3.1 32.7 1.0 N A:CYS379 3.6 32.7 1.0 CA A:CYS379 3.7 32.7 1.0 C A:CYS379 3.8 32.7 1.0 S4 A:SF4501 3.9 37.0 1.0 N A:GLN381 4.0 27.9 1.0 CA A:GLY380 4.1 27.0 1.0 OG A:SER378 4.3 36.3 1.0 CG A:GLN381 4.3 27.9 1.0 CB A:CYS425 4.3 33.2 1.0 CD A:PRO223 4.3 33.6 1.0 SG A:CYS382 4.4 23.4 1.0 C A:GLY380 4.4 27.0 1.0 NE2 A:GLN381 4.6 27.9 1.0 SG A:CYS385 4.7 30.1 1.0 C A:SER378 4.7 36.3 1.0 CG A:PRO223 4.8 33.6 1.0 SG A:CYS425 4.9 33.2 1.0 CD1 A:ILE205 4.9 40.6 1.0 CB A:CYS385 4.9 30.1 1.0 N A:CYS382 4.9 23.4 1.0 O A:CYS379 5.0 32.7 1.0

Iron binding site 5 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:30.0 occ:1.00 FE1 B:SF4301 0.0 30.0 1.0 SG B:CYS111 1.9 17.3 1.0 S4 B:SF4301 2.3 30.0 1.0 S3 B:SF4301 2.3 30.0 1.0 S2 B:SF4301 2.3 30.0 1.0 FE2 B:SF4301 2.7 30.0 1.0 FE3 B:SF4301 2.7 30.0 1.0 FE4 B:SF4301 2.7 30.0 1.0 CB B:CYS111 3.1 17.3 1.0 CA B:CYS111 3.4 17.3 1.0 S1 B:SF4301 3.9 30.0 1.0 N B:ILE112 4.0 13.3 1.0 CE2 B:TYR143 4.1 15.1 1.0 C B:CYS111 4.1 17.3 1.0 CB B:ALA164 4.3 13.0 1.0 N B:ALA113 4.3 12.8 1.0 N B:CYS114 4.7 12.1 1.0 CD2 B:TYR143 4.7 15.1 1.0 N B:CYS111 4.7 17.3 1.0 SG B:CYS160 4.7 11.7 1.0 SG B:CYS114 4.8 12.1 1.0 CZ B:TYR143 4.8 15.1 1.0 OH B:TYR143 4.8 15.1 1.0 CA B:ALA113 4.9 12.8 1.0

Iron binding site 6 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:30.0 occ:1.00 FE2 B:SF4301 0.0 30.0 1.0 SG B:CYS114 2.3 12.1 1.0 S3 B:SF4301 2.3 30.0 1.0 S1 B:SF4301 2.3 30.0 1.0 S4 B:SF4301 2.3 30.0 1.0 FE4 B:SF4301 2.7 30.0 1.0 FE3 B:SF4301 2.7 30.0 1.0 FE1 B:SF4301 2.7 30.0 1.0 CB B:CYS114 3.7 12.1 1.0 N B:CYS114 3.7 12.1 1.0 C B:CYS114 3.8 12.1 1.0 O B:CYS114 3.8 12.1 1.0 S2 B:SF4301 3.9 30.0 1.0 CA B:CYS114 3.9 12.1 1.0 N B:LEU116 4.3 13.6 1.0 N B:LYS115 4.3 13.7 1.0 SG B:CYS111 4.4 17.3 1.0 SG B:CYS160 4.6 11.7 1.0 CB B:LEU116 4.7 13.6 1.0 C B:ALA113 4.9 12.8 1.0 CG B:LEU116 4.9 13.6 1.0 CD B:PRO161 4.9 11.1 1.0 CA B:LYS115 4.9 13.7 1.0 CB B:CYS160 5.0 11.7 1.0 N B:ALA113 5.0 12.8 1.0

Iron binding site 7 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:30.0 occ:1.00 FE3 B:SF4301 0.0 30.0 1.0 S1 B:SF4301 2.3 30.0 1.0 S4 B:SF4301 2.3 30.0 1.0 S2 B:SF4301 2.3 30.0 1.0 FE2 B:SF4301 2.7 30.0 1.0 FE1 B:SF4301 2.7 30.0 1.0 FE4 B:SF4301 2.7 30.0 1.0 OH B:TYR143 2.9 15.1 1.0 CE2 B:TYR143 3.2 15.1 1.0 CZ B:TYR143 3.5 15.1 1.0 S3 B:SF4301 3.9 30.0 1.0 CD1 B:ILE128 4.1 14.5 1.0 CG2 B:ILE165 4.1 11.1 1.0 SG B:CYS111 4.3 17.3 1.0 CD2 B:TYR143 4.4 15.1 1.0 CB B:CYS117 4.7 15.0 1.0 CE1 B:TYR143 4.8 15.1 1.0 CB B:ILE165 4.8 11.1 1.0 SG B:CYS114 4.9 12.1 1.0 N B:CYS117 4.9 15.0 1.0 SG B:CYS160 4.9 11.7 1.0 CB B:CYS160 5.0 11.7 1.0

Iron binding site 8 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:30.0 occ:1.00 FE4 B:SF4301 0.0 30.0 1.0 SG B:CYS160 2.3 11.7 1.0 S3 B:SF4301 2.3 30.0 1.0 S1 B:SF4301 2.3 30.0 1.0 S2 B:SF4301 2.3 30.0 1.0 FE2 B:SF4301 2.7 30.0 1.0 FE3 B:SF4301 2.7 30.0 1.0 FE1 B:SF4301 2.7 30.0 1.0 CB B:CYS160 3.0 11.7 1.0 CB B:ALA164 3.7 13.0 1.0 CA B:CYS160 3.8 11.7 1.0 S4 B:SF4301 3.9 30.0 1.0 CG2 B:ILE165 4.0 11.1 1.0 N B:ILE165 4.3 11.1 1.0 N B:ALA164 4.5 13.0 1.0 CG2 B:VAL162 4.5 12.4 1.0 SG B:CYS114 4.5 12.1 1.0 SG B:CYS111 4.6 17.3 1.0 CA B:ALA164 4.6 13.0 1.0 C B:CYS160 4.7 11.7 1.0 CB B:ILE165 4.8 11.1 1.0 CD B:PRO161 4.9 11.1 1.0 N B:CYS160 4.9 11.7 1.0 C B:ALA164 4.9 13.0 1.0 CA B:CYS111 4.9 17.3 1.0 OH B:TYR143 5.0 15.1 1.0

Iron binding site 9 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe302 b:30.0 occ:1.00 FE1 B:SF4302 0.0 30.0 1.0 SG B:CYS156 2.2 12.7 1.0 SG B:CYS121 2.3 12.5 1.0 S2 B:SF4302 2.3 30.0 1.0 S4 B:SF4302 2.3 30.0 1.0 S3 B:SF4302 2.3 30.0 1.0 SG B:CYS117 2.3 15.0 1.0 FE3 B:SF4302 2.7 30.0 1.0 FE4 B:SF4302 2.7 30.0 1.0 FE2 B:SF4302 2.7 30.0 1.0 CB B:CYS156 3.3 12.7 1.0 CB B:CYS121 3.5 12.5 1.0 S1 B:SF4302 3.9 30.0 1.0 CG1 B:ILE126 3.9 12.1 1.0 CD1 B:ILE126 4.2 12.1 1.0 CB B:CYS117 4.2 15.0 1.0 CA B:CYS121 4.2 12.5 1.0 NE2 B:HIS99 4.3 14.2 1.0 N B:CYS156 4.3 12.7 1.0 CA B:CYS156 4.5 12.7 1.0 CD1 B:ILE145 4.5 13.8 1.0 CD2 B:HIS99 4.8 14.2 1.0 SG B:CYS150 4.8 10.2 1.0 N B:CYS121 4.9 12.5 1.0 SG B:CYS153 4.9 12.4 1.0 CB B:ILE126 5.0 12.1 1.0

Iron binding site 10 out of 28 in the Human Kidney Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Human Kidney Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe302 b:30.0 occ:1.00 FE2 B:SF4302 0.0 30.0 1.0 NE2 B:HIS99 2.1 14.2 1.0 SG B:CYS150 2.3 10.2 1.0 S1 B:SF4302 2.3 30.0 1.0 S4 B:SF4302 2.3 30.0 1.0 S3 B:SF4302 2.3 30.0 1.0 FE4 B:SF4302 2.7 30.0 1.0 FE3 B:SF4302 2.7 30.0 1.0 FE1 B:SF4302 2.7 30.0 1.0 CE1 B:HIS99 2.9 14.2 1.0 CD2 B:HIS99 3.2 14.2 1.0 CD1 B:ILE145 3.3 13.8 1.0 CB B:CYS150 3.8 10.2 1.0 S2 B:SF4302 3.9 30.0 1.0 ND1 B:HIS99 4.0 14.2 1.0 CG B:HIS99 4.2 14.2 1.0 OE1 B:GLU167 4.4 13.5 1.0 CG1 B:ILE145 4.6 13.8 1.0 CA B:CYS150 4.7 10.2 1.0 OE2 B:GLU167 4.7 13.5 1.0 SG B:CYS153 4.7 12.4 1.0 SG B:CYS121 4.7 12.5 1.0 N B:TYR152 4.8 11.9 1.0 SG B:CYS156 4.8 12.7 1.0 CA B:TYR152 4.9 11.9 1.0 SG B:CYS117 4.9 15.0 1.0 CD B:GLU167 4.9 13.5 1.0

Z.Zhang, M.Lyu. Human Kidney Respiratory Complex I To Be Published.