Iron in PDB 9hdl: Crystal Structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) From Neurospora Crassa

The structure of Crystal Structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) From Neurospora Crassa, PDB code: 9hdl was solved by F.Friedrich, F.Genz, O.Einsle, M.Mueller, N.D.Fessner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.82 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	58.105, 61.744, 84.325, 90, 90, 90
R / Rfree (%)	18.1 / 21.3

The binding sites of Iron atom in the Crystal Structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) From Neurospora Crassa (pdb code 9hdl). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) From Neurospora Crassa, PDB code: 9hdl:

Iron binding site 1 out of 1 in the Crystal Structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) From Neurospora Crassa


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) From Neurospora Crassa within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:18.4 occ:1.00 O A:HOH521 2.1 20.3 1.0 NE2 A:HIS229 2.1 19.6 1.0 OD1 A:ASP231 2.2 19.3 1.0 NE2 A:HIS317 2.2 15.8 1.0 O A:HOH657 2.2 24.3 1.0 O A:HOH658 2.2 18.6 1.0 CE1 A:HIS229 3.1 21.0 1.0 CG A:ASP231 3.1 20.0 1.0 CD2 A:HIS317 3.1 20.1 1.0 CD2 A:HIS229 3.2 19.8 1.0 CE1 A:HIS317 3.2 17.3 1.0 OD2 A:ASP231 3.4 19.9 1.0 O A:HOH662 3.8 32.4 1.0 O A:HOH608 4.0 27.4 1.0 OE1 A:GLN299 4.2 20.6 1.0 ND1 A:HIS229 4.2 20.9 1.0 O A:HOH677 4.2 30.4 1.0 CG A:HIS229 4.3 21.0 1.0 CG A:HIS317 4.3 17.4 1.0 ND1 A:HIS317 4.3 18.7 1.0 CB A:ASP231 4.5 16.2 1.0 N A:ASP231 4.8 18.4 1.0 CA A:ASP231 4.9 17.5 1.0 CD A:GLN299 4.9 21.4 1.0

F.Genz, F.Friedrich, C.Lonarz, O.Einsle, M.Jung, M.Muller, N.D.Fessner. Identification and Characterization of Pyrimidine Nucleoside 2'-Hydroxylase Acs Catalysis 2025.
ISSN: ESSN 2155-5435
DOI: 10.1021/ACSCATAL.4C07764