Iron in PDB 9k2g: Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13)

All present enzymatic activity of Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13):
2.7.7.6;

The structure of Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13) also contains other interesting chemical elements:

Zinc	(Zn)	6 atoms
Magnesium	(Mg)	1 atom

The binding sites of Iron atom in the Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13) (pdb code 9k2g). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13), PDB code: 9k2g:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE1 P:SF4401 0.0 101.0 1.0 SG P:CYS290 2.3 103.3 1.0 S3 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 S4 P:SF4401 2.3 101.0 1.0 CB P:CYS290 2.6 103.3 1.0 FE4 P:SF4401 2.7 101.0 1.0 FE2 P:SF4401 2.7 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 S1 P:SF4401 3.9 101.0 1.0 CA P:CYS290 4.1 103.3 1.0 CA P:PHE293 4.4 103.6 1.0 CA P:CYS287 4.4 106.3 1.0 CD2 P:TYR309 4.5 111.4 1.0 SG P:CYS307 4.5 108.3 1.0 N P:PHE293 4.6 103.6 1.0 CB P:CYS296 4.7 104.5 1.0 CG1 P:VAL292 4.8 97.3 1.0 SG P:CYS287 4.8 106.3 1.0 C P:VAL292 4.8 97.3 1.0 O P:PRO286 4.8 105.3 1.0 CB P:PHE293 4.9 103.6 1.0 CE2 P:TYR309 4.9 111.4 1.0 C P:CYS290 4.9 103.3 1.0 CB P:CYS287 4.9 106.3 1.0 O P:VAL292 4.9 97.3 1.0 N P:CYS290 4.9 103.3 1.0 SG P:CYS296 4.9 104.5 1.0

Iron binding site 2 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE2 P:SF4401 0.0 101.0 1.0 SG P:CYS296 2.3 104.5 1.0 S4 P:SF4401 2.3 101.0 1.0 S1 P:SF4401 2.3 101.0 1.0 S3 P:SF4401 2.3 101.0 1.0 CB P:CYS296 2.7 104.5 1.0 FE1 P:SF4401 2.7 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 FE4 P:SF4401 2.7 101.0 1.0 ND2 O:ASN445 3.8 104.9 1.0 S2 P:SF4401 3.9 101.0 1.0 CA P:CYS296 4.0 104.5 1.0 CG O:ASN445 4.6 104.9 1.0 SG P:CYS290 4.6 103.3 1.0 SG P:CYS287 4.8 106.3 1.0 CG2 P:ILE302 4.8 107.9 1.0 N P:CYS296 4.9 104.5 1.0 SG P:CYS307 4.9 108.3 1.0 C P:CYS296 5.0 104.5 1.0

Iron binding site 3 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE3 P:SF4401 0.0 101.0 1.0 SG P:CYS287 2.3 106.3 1.0 S4 P:SF4401 2.3 101.0 1.0 S1 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 FE2 P:SF4401 2.7 101.0 1.0 FE1 P:SF4401 2.7 101.0 1.0 FE4 P:SF4401 2.7 101.0 1.0 CB P:CYS287 3.1 106.3 1.0 CA P:CYS287 3.4 106.3 1.0 ND2 O:ASN445 3.5 104.9 1.0 CE P:MET310 3.8 117.8 1.0 S3 P:SF4401 3.9 101.0 1.0 N P:CYS287 4.0 106.3 1.0 CG O:ASN445 4.3 104.9 1.0 CB O:ASN445 4.3 104.9 1.0 SG P:CYS296 4.5 104.5 1.0 CB P:CYS290 4.6 103.3 1.0 C P:CYS287 4.7 106.3 1.0 C P:PRO286 4.7 105.3 1.0 SG P:CYS307 4.7 108.3 1.0 SG P:CYS290 4.9 103.3 1.0 O P:CYS287 4.9 106.3 1.0 O P:PRO286 5.0 105.3 1.0

Iron binding site 4 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Human Rna Polymerase III De Novo Transcribing Complex 13 (TC13) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE4 P:SF4401 0.0 101.0 1.0 SG P:CYS307 2.3 108.3 1.0 S3 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 S1 P:SF4401 2.3 101.0 1.0 FE1 P:SF4401 2.7 101.0 1.0 FE2 P:SF4401 2.7 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 CB P:CYS307 3.2 108.3 1.0 CE P:MET310 3.5 117.8 1.0 S4 P:SF4401 3.9 101.0 1.0 CD2 P:TYR309 4.3 111.4 1.0 CA P:CYS307 4.5 108.3 1.0 SG P:CYS296 4.6 104.5 1.0 SG P:CYS290 4.7 103.3 1.0 SG P:CYS287 4.7 106.3 1.0 CA P:PRO304 4.8 105.5 1.0 CE2 Q:PHE38 4.9 109.3 1.0 CB P:TYR309 4.9 111.4 1.0 O P:SER303 5.0 107.8 1.0

Q.Wang, Y.Ren, Q.Jin, X.Chen, Y.Xu. Human Rna Polymerase III De Novo Transcribing Complex 14 (TC14) To Be Published.