Iron in PDB 9k3b: Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall)

All present enzymatic activity of Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall):
2.7.7.6;

The structure of Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall) also contains other interesting chemical elements:

Zinc	(Zn)	6 atoms
Magnesium	(Mg)	1 atom

The binding sites of Iron atom in the Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall) (pdb code 9k3b). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall), PDB code: 9k3b:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE1 P:SF4401 0.0 101.0 1.0 S4 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 S3 P:SF4401 2.3 101.0 1.0 FE4 P:SF4401 2.7 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 FE2 P:SF4401 2.7 101.0 1.0 SG P:CYS290 2.9 103.3 1.0 CD2 P:TYR309 3.2 111.4 1.0 CB P:CYS290 3.6 103.3 1.0 CE2 P:TYR309 3.7 111.4 1.0 SG P:CYS307 3.8 108.3 1.0 S1 P:SF4401 3.9 101.0 1.0 CG P:TYR309 4.0 111.4 1.0 CB P:TYR309 4.3 111.4 1.0 CZ P:TYR309 4.8 111.4 1.0 O P:PRO286 4.9 105.3 1.0 CE2 Q:PHE38 4.9 109.3 1.0 CD2 Q:PHE38 4.9 109.3 1.0 CA P:CYS290 4.9 103.3 1.0 CG1 P:VAL292 4.9 97.3 1.0 CD1 P:TYR309 5.0 111.4 1.0

Iron binding site 2 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE2 P:SF4401 0.0 101.0 1.0 S1 P:SF4401 2.3 101.0 1.0 S4 P:SF4401 2.3 101.0 1.0 S3 P:SF4401 2.3 101.0 1.0 FE4 P:SF4401 2.7 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 FE1 P:SF4401 2.7 101.0 1.0 CG2 P:ILE302 3.7 107.9 1.0 S2 P:SF4401 3.9 101.0 1.0 CB P:CYS296 4.1 104.5 1.0 SG P:CYS296 4.1 104.5 1.0 SG P:CYS290 4.5 103.3 1.0 CA P:CYS296 4.7 104.5 1.0 SG P:CYS307 4.7 108.3 1.0 CE2 Q:PHE38 4.9 109.3 1.0

Iron binding site 3 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE3 P:SF4401 0.0 101.0 1.0 S1 P:SF4401 2.3 101.0 1.0 S4 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 FE1 P:SF4401 2.7 101.0 1.0 FE2 P:SF4401 2.7 101.0 1.0 FE4 P:SF4401 2.7 101.0 1.0 SG P:CYS287 3.6 106.3 1.0 S3 P:SF4401 3.9 101.0 1.0 CA P:CYS287 3.9 106.3 1.0 CB P:CYS287 4.0 106.3 1.0 ND2 O:ASN445 4.4 104.9 1.0 N P:CYS287 4.5 106.3 1.0 SG P:CYS307 4.6 108.3 1.0 CB P:CYS290 4.6 103.3 1.0 SG P:CYS290 4.7 103.3 1.0 CE P:MET310 4.8 117.8 1.0 O P:PRO286 4.8 105.3 1.0 C P:PRO286 4.9 105.3 1.0 CB O:ASN445 4.9 104.9 1.0 CG O:ASN445 5.0 104.9 1.0

Iron binding site 4 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Human Rna Polymerase III De Novo Transcribing Complex 10 Overall (TC10-Overall) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE4 P:SF4401 0.0 101.0 1.0 SG P:CYS307 2.2 108.3 1.0 S1 P:SF4401 2.3 101.0 1.0 S3 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 FE2 P:SF4401 2.7 101.0 1.0 FE1 P:SF4401 2.7 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 CB P:CYS307 2.8 108.3 1.0 CE P:MET310 3.9 117.8 1.0 S4 P:SF4401 3.9 101.0 1.0 CA P:CYS307 4.0 108.3 1.0 CA P:PRO304 4.4 105.5 1.0 CD2 P:TYR309 4.5 111.4 1.0 O P:SER303 4.5 107.8 1.0 CG P:MET310 4.5 117.8 1.0 SD P:MET310 4.8 117.8 1.0 CE2 Q:PHE38 4.8 109.3 1.0 N P:PRO304 4.9 105.5 1.0 CB P:TYR309 4.9 111.4 1.0 C P:CYS307 4.9 108.3 1.0 C P:SER303 5.0 107.8 1.0

Q.Wang, Y.Ren, Q.Jin, X.Chen, Y.Xu. Human Rna Polymerase III De Novo Transcribing Complex 10-Overall To Be Published.