Iron in PDB 1e5i: Delta-R306 Deacetoxycephalosporin C Synthase Complexed with Iron and 2-Oxoglutarate.

All present enzymatic activity of Delta-R306 Deacetoxycephalosporin C Synthase Complexed with Iron and 2-Oxoglutarate.:
1.14.20.1;

The structure of Delta-R306 Deacetoxycephalosporin C Synthase Complexed with Iron and 2-Oxoglutarate., PDB code: 1e5i was solved by H.J.Lee, M.D.Lloyd, K.Harlos, I.J.Clifton, J.E.Baldwin, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.99 / 2.10
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	105.787, 105.787, 71.222, 90.00, 90.00, 120.00
R / Rfree (%)	22.7 / 24.2

The binding sites of Iron atom in the Delta-R306 Deacetoxycephalosporin C Synthase Complexed with Iron and 2-Oxoglutarate. (pdb code 1e5i). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Delta-R306 Deacetoxycephalosporin C Synthase Complexed with Iron and 2-Oxoglutarate., PDB code: 1e5i:

Iron binding site 1 out of 1 in the Delta-R306 Deacetoxycephalosporin C Synthase Complexed with Iron and 2-Oxoglutarate.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Delta-R306 Deacetoxycephalosporin C Synthase Complexed with Iron and 2-Oxoglutarate. within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe901 b:31.8 occ:1.00 O2 A:AKG902 2.1 32.7 1.0 NE2 A:HIS243 2.2 28.4 1.0 NE2 A:HIS183 2.3 33.9 1.0 OD1 A:ASP185 2.3 28.5 1.0 O5 A:AKG902 2.3 31.6 1.0 O A:HOH2074 2.3 27.6 1.0 OD2 A:ASP185 2.6 29.4 1.0 CG A:ASP185 2.8 28.7 1.0 C1 A:AKG902 3.0 31.4 1.0 CD2 A:HIS243 3.1 26.0 1.0 C2 A:AKG902 3.1 31.6 1.0 CE1 A:HIS183 3.2 33.7 1.0 CE1 A:HIS243 3.3 26.5 1.0 CD2 A:HIS183 3.3 32.4 1.0 CG2 A:ILE305 4.1 24.9 1.0 CG A:HIS243 4.3 27.0 1.0 O1 A:AKG902 4.3 32.2 1.0 CB A:ASP185 4.3 27.6 1.0 ND1 A:HIS243 4.3 27.0 1.0 ND1 A:HIS183 4.3 35.1 1.0 CG A:HIS183 4.4 34.4 1.0 C3 A:AKG902 4.6 31.4 1.0 CE1 A:PHE264 4.8 24.4 1.0 N A:ASP185 4.9 28.4 1.0 CA A:ASP185 5.0 27.3 1.0

H.J.Lee, M.D.Lloyd, K.Harlos, I.J.Clifton, J.E.Baldwin, C.J.Schofield. Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs) J.Mol.Biol. V. 308 937 2001.
ISSN: ISSN 0022-2836
PubMed: 11352583
DOI: 10.1006/JMBI.2001.4649