Atomistry » Iron » PDB 1j3z-1jju » 1jeb
Atomistry »
  Iron »
    PDB 1j3z-1jju »
      1jeb »

Iron in PDB 1jeb: Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2)

Protein crystallography data

The structure of Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2), PDB code: 1jeb was solved by R.D.Kidd, J.E.Russell, N.J.Watmough, E.N.Baker, T.Brittain, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.00 / 2.10
Space group P 41
Cell size a, b, c (Å), α, β, γ (°) 84.921, 84.921, 104.523, 90.00, 90.00, 90.00
R / Rfree (%) 21.6 / 24.9

Iron Binding Sites:

The binding sites of Iron atom in the Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2) (pdb code 1jeb). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2), PDB code: 1jeb:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in 1jeb

Go back to Iron Binding Sites List in 1jeb
Iron binding site 1 out of 4 in the Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe142

b:34.9
occ:1.00
FE A:HEM142 0.0 34.9 1.0
C A:CMO143 1.8 62.7 1.0
NA A:HEM142 2.0 34.7 1.0
NB A:HEM142 2.0 33.0 1.0
NC A:HEM142 2.0 32.3 1.0
ND A:HEM142 2.0 34.4 1.0
NE2 A:HIS87 2.3 33.8 1.0
O A:CMO143 2.8 62.4 1.0
C1A A:HEM142 3.0 35.8 1.0
C1B A:HEM142 3.0 33.0 1.0
C4D A:HEM142 3.0 35.1 1.0
C4B A:HEM142 3.0 31.8 1.0
C4A A:HEM142 3.0 35.3 1.0
C1C A:HEM142 3.1 31.8 1.0
C4C A:HEM142 3.1 32.0 1.0
C1D A:HEM142 3.1 33.8 1.0
CD2 A:HIS87 3.2 32.7 1.0
CE1 A:HIS87 3.3 34.2 1.0
CHA A:HEM142 3.3 35.8 1.0
CHB A:HEM142 3.4 33.6 1.0
CHC A:HEM142 3.4 32.4 1.0
CHD A:HEM142 3.4 33.5 1.0
C2A A:HEM142 4.3 37.0 1.0
C2B A:HEM142 4.3 32.5 1.0
C3B A:HEM142 4.3 31.7 1.0
C3A A:HEM142 4.3 36.0 1.0
C3C A:HEM142 4.3 31.7 1.0
C2C A:HEM142 4.3 32.0 1.0
C3D A:HEM142 4.3 35.0 1.0
C2D A:HEM142 4.3 34.5 1.0
CG A:HIS87 4.4 33.0 1.0
ND1 A:HIS87 4.4 34.0 1.0
CE1 A:HIS58 4.5 45.2 1.0
NE2 A:HIS58 4.6 44.5 1.0

Iron binding site 2 out of 4 in 1jeb

Go back to Iron Binding Sites List in 1jeb
Iron binding site 2 out of 4 in the Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Fe147

b:60.1
occ:1.00
FE B:HEM147 0.0 60.1 1.0
C B:CMO148 1.7 20.3 1.0
NA B:HEM147 2.0 61.0 1.0
NB B:HEM147 2.0 60.1 1.0
ND B:HEM147 2.0 60.7 1.0
NC B:HEM147 2.0 60.5 1.0
NE2 B:HIS92 2.5 75.2 1.0
O B:CMO148 2.7 22.2 1.0
C1A B:HEM147 3.0 61.0 1.0
C4D B:HEM147 3.0 61.6 1.0
C1B B:HEM147 3.0 60.0 1.0
C4B B:HEM147 3.1 59.9 1.0
C4A B:HEM147 3.1 60.9 1.0
C1C B:HEM147 3.1 59.8 1.0
C4C B:HEM147 3.1 60.2 1.0
C1D B:HEM147 3.1 61.2 1.0
CD2 B:HIS92 3.2 75.4 1.0
CHA B:HEM147 3.4 61.1 1.0
CHB B:HEM147 3.4 60.5 1.0
CHC B:HEM147 3.4 59.7 1.0
CHD B:HEM147 3.5 60.6 1.0
CE1 B:HIS92 3.7 75.6 1.0
C3B B:HEM147 4.3 59.8 1.0
C2B B:HEM147 4.3 59.9 1.0
C2A B:HEM147 4.3 61.8 1.0
C3D B:HEM147 4.3 62.4 1.0
C3A B:HEM147 4.3 61.6 1.0
NE2 B:HIS63 4.3 65.2 1.0
C3C B:HEM147 4.3 60.1 1.0
C2C B:HEM147 4.3 60.1 1.0
C2D B:HEM147 4.4 61.9 1.0
CG B:HIS92 4.5 75.3 1.0
CG2 B:VAL67 4.6 64.9 1.0
ND1 B:HIS92 4.7 75.4 1.0

Iron binding site 3 out of 4 in 1jeb

Go back to Iron Binding Sites List in 1jeb
Iron binding site 3 out of 4 in the Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Fe142

b:37.6
occ:1.00
FE C:HEM142 0.0 37.6 1.0
C C:CMO143 1.8 69.6 1.0
NA C:HEM142 2.0 38.2 1.0
NB C:HEM142 2.0 37.6 1.0
NC C:HEM142 2.0 37.2 1.0
ND C:HEM142 2.0 38.4 1.0
NE2 C:HIS87 2.2 42.9 1.0
O C:CMO143 2.9 68.6 1.0
C1A C:HEM142 3.0 38.2 1.0
C4D C:HEM142 3.0 38.0 1.0
C4B C:HEM142 3.0 36.8 1.0
C1B C:HEM142 3.0 37.3 1.0
C1C C:HEM142 3.1 37.8 1.0
C4A C:HEM142 3.1 37.5 1.0
C4C C:HEM142 3.1 37.1 1.0
CD2 C:HIS87 3.1 43.4 1.0
C1D C:HEM142 3.1 37.6 1.0
CE1 C:HIS87 3.2 44.0 1.0
CHA C:HEM142 3.3 38.0 1.0
CHC C:HEM142 3.4 37.4 1.0
CHB C:HEM142 3.4 38.1 1.0
CHD C:HEM142 3.5 37.2 1.0
C2A C:HEM142 4.3 38.8 1.0
ND1 C:HIS87 4.3 45.0 1.0
CG C:HIS87 4.3 44.3 1.0
C3A C:HEM142 4.3 37.9 1.0
C3B C:HEM142 4.3 37.6 1.0
C2B C:HEM142 4.3 37.6 1.0
C3D C:HEM142 4.3 38.9 1.0
C2C C:HEM142 4.3 37.2 1.0
C3C C:HEM142 4.3 36.4 1.0
C2D C:HEM142 4.4 37.7 1.0
CE1 C:HIS58 4.4 46.3 1.0
NE2 C:HIS58 4.6 45.3 1.0
CG2 C:VAL62 4.9 37.5 1.0

Iron binding site 4 out of 4 in 1jeb

Go back to Iron Binding Sites List in 1jeb
Iron binding site 4 out of 4 in the Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Chimeric Human/Mouse Carbonmonoxy Hemoglobin (Human ZETA2 / Mouse BETA2) within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Fe147

b:33.3
occ:1.00
FE D:HEM147 0.0 33.3 1.0
C D:CMO148 1.9 43.2 1.0
NB D:HEM147 2.0 31.2 1.0
NA D:HEM147 2.0 33.3 1.0
ND D:HEM147 2.0 33.2 1.0
NC D:HEM147 2.0 32.0 1.0
NE2 D:HIS92 2.2 40.1 1.0
O D:CMO148 2.9 41.5 1.0
C4D D:HEM147 3.0 35.3 1.0
C1A D:HEM147 3.0 34.7 1.0
C4B D:HEM147 3.0 31.0 1.0
C1B D:HEM147 3.1 31.7 1.0
C1C D:HEM147 3.1 31.0 1.0
C4A D:HEM147 3.1 33.8 1.0
C4C D:HEM147 3.1 32.4 1.0
C1D D:HEM147 3.1 34.5 1.0
CE1 D:HIS92 3.1 39.4 1.0
CD2 D:HIS92 3.1 39.0 1.0
CHA D:HEM147 3.3 34.5 1.0
CHC D:HEM147 3.4 30.5 1.0
CHB D:HEM147 3.5 31.5 1.0
CHD D:HEM147 3.5 32.5 1.0
ND1 D:HIS92 4.2 39.5 1.0
C3B D:HEM147 4.3 31.8 1.0
C3D D:HEM147 4.3 37.0 1.0
C2A D:HEM147 4.3 37.2 1.0
CG D:HIS92 4.3 39.7 1.0
NE2 D:HIS63 4.3 40.6 1.0
C2B D:HEM147 4.3 31.2 1.0
C3A D:HEM147 4.3 35.6 1.0
C2D D:HEM147 4.3 35.0 1.0
C2C D:HEM147 4.3 32.9 1.0
C3C D:HEM147 4.3 32.9 1.0
CG2 D:VAL67 4.8 31.9 1.0
CE1 D:HIS63 4.9 41.5 1.0

Reference:

R.D.Kidd, J.E.Russell, N.J.Watmough, E.N.Baker, T.Brittain. The Role of Beta Chains in the Control of the Hemoglobin Oxygen Binding Function: Chimeric Human/Mouse Proteins, Structure, and Function. Biochemistry V. 40 15669 2001.
ISSN: ISSN 0006-2960
PubMed: 11747442
DOI: 10.1021/BI011329F
Page generated: Sat Aug 3 08:27:53 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy