Iron in PDB 1sox: Sulfite Oxidase From Chicken Liver

All present enzymatic activity of Sulfite Oxidase From Chicken Liver:
1.8.3.1;

The structure of Sulfite Oxidase From Chicken Liver, PDB code: 1sox was solved by C.Kisker, H.Schindelin, D.C.Rees, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	55.117, 197.690, 56.009, 90.00, 94.23, 90.00
R / Rfree (%)	17.5 / 22

The structure of Sulfite Oxidase From Chicken Liver also contains other interesting chemical elements:

Molybdenum

(Mo)

2 atoms

The binding sites of Iron atom in the Sulfite Oxidase From Chicken Liver (pdb code 1sox). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Sulfite Oxidase From Chicken Liver, PDB code: 1sox:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Sulfite Oxidase From Chicken Liver


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Sulfite Oxidase From Chicken Liver within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe502 b:22.7 occ:1.00 FE A:HEM502 0.0 22.7 1.0 NB A:HEM502 2.0 21.7 1.0 NA A:HEM502 2.0 22.6 1.0 NC A:HEM502 2.0 18.2 1.0 ND A:HEM502 2.0 21.0 1.0 NE2 A:HIS40 2.0 20.6 1.0 NE2 A:HIS65 2.1 20.2 1.0 CE1 A:HIS40 3.0 23.1 1.0 CD2 A:HIS65 3.0 20.7 1.0 C1C A:HEM502 3.0 17.4 1.0 C1A A:HEM502 3.0 23.0 1.0 C4C A:HEM502 3.0 16.2 1.0 C4A A:HEM502 3.0 23.2 1.0 C1B A:HEM502 3.1 24.5 1.0 C1D A:HEM502 3.1 20.1 1.0 C4B A:HEM502 3.1 22.5 1.0 CD2 A:HIS40 3.1 21.0 1.0 C4D A:HEM502 3.1 24.3 1.0 CE1 A:HIS65 3.1 23.1 1.0 CHD A:HEM502 3.4 21.6 1.0 CHB A:HEM502 3.4 23.5 1.0 CHA A:HEM502 3.4 22.9 1.0 CHC A:HEM502 3.4 17.7 1.0 ND1 A:HIS40 4.2 22.9 1.0 ND1 A:HIS65 4.2 19.9 1.0 CG A:HIS65 4.2 20.0 1.0 CG A:HIS40 4.2 23.2 1.0 C2A A:HEM502 4.3 22.6 1.0 C2C A:HEM502 4.3 17.6 1.0 C3A A:HEM502 4.3 22.5 1.0 C3C A:HEM502 4.3 19.2 1.0 C2B A:HEM502 4.3 21.2 1.0 C3B A:HEM502 4.3 22.4 1.0 C2D A:HEM502 4.3 24.0 1.0 C3D A:HEM502 4.3 26.5 1.0

Iron binding site 2 out of 2 in the Sulfite Oxidase From Chicken Liver


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Sulfite Oxidase From Chicken Liver within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe502 b:31.9 occ:1.00 FE B:HEM502 0.0 31.9 1.0 ND B:HEM502 2.0 35.9 1.0 NA B:HEM502 2.0 35.0 1.0 NC B:HEM502 2.0 32.9 1.0 NB B:HEM502 2.0 33.6 1.0 NE2 B:HIS40 2.0 23.1 1.0 NE2 B:HIS65 2.0 25.2 1.0 CE1 B:HIS65 2.7 31.2 1.0 CD2 B:HIS40 3.0 25.3 1.0 C1A B:HEM502 3.0 37.5 1.0 C4D B:HEM502 3.1 37.4 1.0 C1C B:HEM502 3.1 32.3 1.0 C1D B:HEM502 3.1 37.6 1.0 C4C B:HEM502 3.1 31.0 1.0 C4B B:HEM502 3.1 32.9 1.0 C4A B:HEM502 3.1 36.8 1.0 C1B B:HEM502 3.1 33.1 1.0 CE1 B:HIS40 3.1 24.2 1.0 CD2 B:HIS65 3.3 31.5 1.0 CHA B:HEM502 3.4 35.0 1.0 CHD B:HEM502 3.4 34.2 1.0 CHC B:HEM502 3.4 32.4 1.0 CHB B:HEM502 3.5 36.8 1.0 ND1 B:HIS65 4.0 31.2 1.0 CG B:HIS40 4.2 27.6 1.0 ND1 B:HIS40 4.2 25.6 1.0 CG B:HIS65 4.3 31.8 1.0 C2A B:HEM502 4.3 37.7 1.0 C3D B:HEM502 4.3 40.0 1.0 C2D B:HEM502 4.3 38.2 1.0 C2C B:HEM502 4.3 29.9 1.0 C3A B:HEM502 4.3 38.9 1.0 C3B B:HEM502 4.3 33.5 1.0 C2B B:HEM502 4.3 33.6 1.0 C3C B:HEM502 4.3 32.0 1.0

C.Kisker, H.Schindelin, A.Pacheco, W.A.Wehbi, R.M.Garrett, K.V.Rajagopalan, J.H.Enemark, D.C.Rees. Molecular Basis of Sulfite Oxidase Deficiency From the Structure of Sulfite Oxidase. Cell(Cambridge,Mass.) V. 91 973 1997.
ISSN: ISSN 0092-8674
PubMed: 9428520
DOI: 10.1016/S0092-8674(00)80488-2