Iron in PDB 6d05: Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2.

The structure of Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2. also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Iron atom in the Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2. (pdb code 6d05). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2., PDB code: 6d05:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2. within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe701 b:74.1 occ:1.00 OH C:TYR517 2.1 68.9 1.0 O3 C:CO3702 2.1 71.8 1.0 O1 C:CO3702 2.1 71.8 1.0 NE2 C:HIS585 2.1 63.5 1.0 OH C:TYR426 2.2 74.1 1.0 C C:CO3702 2.3 71.8 1.0 NH1 C:ARG632 2.7 67.2 1.0 CE1 C:HIS585 2.9 63.5 1.0 CZ C:TYR426 3.2 74.1 1.0 CZ C:TYR517 3.3 68.9 1.0 CD2 C:HIS585 3.3 63.5 1.0 O2 C:CO3702 3.4 71.8 1.0 OG1 C:THR457 3.8 71.3 1.0 CE1 C:TYR426 3.9 74.1 1.0 CB C:ASP392 3.9 60.3 1.0 CZ C:ARG632 3.9 67.2 1.0 CE2 C:TYR426 4.0 74.1 1.0 CE1 C:TYR517 4.0 68.9 1.0 ND1 C:HIS585 4.1 63.5 1.0 CE2 C:TYR517 4.2 68.9 1.0 CG C:HIS585 4.3 63.5 1.0 OD2 C:ASP392 4.5 60.3 1.0 NE C:ARG632 4.5 67.2 1.0 NH1 C:ARG456 4.5 68.5 1.0 CG C:ASP392 4.7 60.3 1.0 NH2 C:ARG632 4.9 67.2 1.0

Iron binding site 2 out of 4 in the Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2. within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe703 b:70.8 occ:1.00 OH C:TYR95 2.1 64.9 1.0 OD1 C:ASP63 2.1 48.9 1.0 O2 C:CO3704 2.1 56.9 1.0 OH C:TYR188 2.1 66.1 1.0 NE2 C:HIS249 2.2 53.2 1.0 O3 C:CO3704 2.3 56.9 1.0 C C:CO3704 2.4 56.9 1.0 CG C:ASP63 3.0 48.9 1.0 CD2 C:HIS249 3.0 53.2 1.0 CE1 C:HIS249 3.2 53.2 1.0 CZ C:TYR95 3.4 64.9 1.0 CZ C:TYR188 3.4 66.1 1.0 OG C:SER125 3.4 52.3 1.0 OD2 C:ASP63 3.5 48.9 1.0 O1 C:CO3704 3.6 56.9 1.0 CE1 C:TYR188 4.0 66.1 1.0 CE1 C:TYR95 4.1 64.9 1.0 CB C:ASP63 4.1 48.9 1.0 CG C:HIS249 4.2 53.2 1.0 ND1 C:HIS249 4.3 53.2 1.0 CE2 C:TYR95 4.3 64.9 1.0 CE2 C:TYR188 4.5 66.1 1.0 NZ C:LYS296 4.5 70.5 1.0 NH2 C:ARG124 4.5 52.6 1.0 CA C:ASP63 4.7 48.9 1.0 CB C:SER125 4.7 52.3 1.0 CE C:LYS296 4.9 70.5 1.0

Iron binding site 3 out of 4 in the Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2. within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe701 b:71.3 occ:1.00 OH D:TYR517 2.1 68.9 1.0 O3 D:CO3702 2.1 71.8 1.0 O1 D:CO3702 2.1 71.8 1.0 NE2 D:HIS585 2.1 59.6 1.0 OH D:TYR426 2.2 72.2 1.0 C D:CO3702 2.3 71.8 1.0 NH1 D:ARG632 2.6 64.5 1.0 CE1 D:HIS585 2.9 59.6 1.0 CZ D:TYR426 3.2 72.2 1.0 CZ D:TYR517 3.3 68.9 1.0 CD2 D:HIS585 3.3 59.6 1.0 O2 D:CO3702 3.4 71.8 1.0 OG1 D:THR457 3.9 70.0 1.0 CE1 D:TYR426 3.9 72.2 1.0 CZ D:ARG632 3.9 64.5 1.0 CB D:ASP392 3.9 56.2 1.0 CE2 D:TYR426 4.0 72.2 1.0 CE1 D:TYR517 4.0 68.9 1.0 ND1 D:HIS585 4.1 59.6 1.0 CE2 D:TYR517 4.1 68.9 1.0 CG D:HIS585 4.3 59.6 1.0 NE D:ARG632 4.5 64.5 1.0 OD2 D:ASP392 4.5 56.2 1.0 NH1 D:ARG456 4.5 66.9 1.0 CG D:ASP392 4.7 56.2 1.0 NH2 D:ARG632 4.9 64.5 1.0

Iron binding site 4 out of 4 in the Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Cryo-Em Structure of A Plasmodium Vivax Invasion Complex Essential For Entry Into Human Reticulocytes; Two Molecules of Parasite Ligand, Subclass 2. within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe703 b:72.3 occ:1.00 OH D:TYR95 2.0 61.8 1.0 O2 D:CO3704 2.1 57.3 1.0 OH D:TYR188 2.1 65.6 1.0 OD1 D:ASP63 2.1 47.1 1.0 NE2 D:HIS249 2.2 50.1 1.0 O3 D:CO3704 2.3 57.3 1.0 C D:CO3704 2.5 57.3 1.0 CG D:ASP63 3.0 47.1 1.0 CD2 D:HIS249 3.1 50.1 1.0 CE1 D:HIS249 3.2 50.1 1.0 CZ D:TYR95 3.4 61.8 1.0 CZ D:TYR188 3.4 65.6 1.0 OG D:SER125 3.4 50.0 1.0 OD2 D:ASP63 3.5 47.1 1.0 O1 D:CO3704 3.7 57.3 1.0 CE1 D:TYR188 4.0 65.6 1.0 CE1 D:TYR95 4.1 61.8 1.0 CB D:ASP63 4.2 47.1 1.0 CG D:HIS249 4.2 50.1 1.0 ND1 D:HIS249 4.3 50.1 1.0 CE2 D:TYR95 4.3 61.8 1.0 CE2 D:TYR188 4.5 65.6 1.0 NZ D:LYS296 4.5 68.4 1.0 NH2 D:ARG124 4.5 52.0 1.0 CA D:ASP63 4.7 47.1 1.0 CB D:SER125 4.7 50.0 1.0 CE D:LYS296 4.9 68.4 1.0

J.Gruszczyk, R.K.Huang, L.J.Chan, S.Menant, C.Hong, J.M.Murphy, Y.F.Mok, M.D.W.Griffin, R.D.Pearson, W.Wong, A.F.Cowman, Z.Yu, W.H.Tham. Cryo-Em Structure of An Essential Plasmodium Vivax Invasion Complex. Nature V. 559 135 2018.
ISSN: ISSN 0028-0836
PubMed: 29950717
DOI: 10.1038/S41586-018-0249-1