Iron in PDB 7jxg: Structural Model For Fe-Containing Human Acireductone Dioxygenase

All present enzymatic activity of Structural Model For Fe-Containing Human Acireductone Dioxygenase:
1.13.11.54;

The binding sites of Iron atom in the Structural Model For Fe-Containing Human Acireductone Dioxygenase (pdb code 7jxg). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structural Model For Fe-Containing Human Acireductone Dioxygenase, PDB code: 7jxg:

Iron binding site 1 out of 1 in the Structural Model For Fe-Containing Human Acireductone Dioxygenase


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structural Model For Fe-Containing Human Acireductone Dioxygenase within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe201 b:0.0 occ:1.00 O A:HOH301 1.9 0.0 1.0 O A:HOH302 1.9 0.0 1.0 OE1 A:GLU94 2.1 0.0 1.0 NE2 A:HIS88 2.1 0.0 1.0 NE2 A:HIS133 2.1 0.0 1.0 NE2 A:HIS90 2.1 0.0 1.0 CE1 A:HIS133 3.1 0.0 1.0 CE1 A:HIS88 3.1 0.0 1.0 CE1 A:HIS90 3.1 0.0 1.0 CD2 A:HIS88 3.1 0.0 1.0 CD2 A:HIS133 3.1 0.0 1.0 CD2 A:HIS90 3.1 0.0 1.0 HE1 A:HIS133 3.3 0.0 1.0 HE1 A:HIS90 3.3 0.0 1.0 HE1 A:HIS88 3.3 0.0 1.0 CD A:GLU94 3.3 0.0 1.0 HD2 A:HIS88 3.4 0.0 1.0 HD2 A:HIS90 3.4 0.0 1.0 HD2 A:HIS133 3.4 0.0 1.0 HG2 A:GLU94 3.8 0.0 1.0 OE2 A:GLU94 4.2 0.0 1.0 CG A:GLU94 4.2 0.0 1.0 ND1 A:HIS133 4.2 0.0 1.0 ND1 A:HIS88 4.2 0.0 1.0 ND1 A:HIS90 4.2 0.0 1.0 CG A:HIS88 4.3 0.0 1.0 CG A:HIS133 4.3 0.0 1.0 CG A:HIS90 4.3 0.0 1.0 HH21 A:ARG96 4.7 0.0 1.0 HE2 A:TYR158 4.7 0.0 1.0 HG3 A:GLU94 4.8 0.0 1.0

X.Liu, A.Garber, J.Ryan, A.Deshpande, D.Ringe, T.C.Pochapsky. A Model For the Solution Structure of Human Fe(II)-Bound Acireductone Dioxygenase and Interactions with the Regulatory Domain of Matrix Metalloproteinase I (Mmp-I). Biochemistry V. 59 4238 2020.
ISSN: ISSN 0006-2960
PubMed: 33135413
DOI: 10.1021/ACS.BIOCHEM.0C00724