Iron in PDB 5ohx: Structure of Active Cystathionine B-Synthase From Apis Mellifera

The structure of Structure of Active Cystathionine B-Synthase From Apis Mellifera, PDB code: 5ohx was solved by P.Gimenez-Mascarell, T.Majtan, I.Oyenarte, J.Ereno-Orbea, J.Majtan, J.P.Kraus, J.Klaudiny, L.A.Martinez-Cruz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.36 / 3.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	86.143, 96.099, 180.684, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 23.1

The binding sites of Iron atom in the Structure of Active Cystathionine B-Synthase From Apis Mellifera (pdb code 5ohx). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of Active Cystathionine B-Synthase From Apis Mellifera, PDB code: 5ohx:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Structure of Active Cystathionine B-Synthase From Apis Mellifera


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of Active Cystathionine B-Synthase From Apis Mellifera within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe701 b:40.5 occ:1.00 FE A:HEM701 0.0 40.5 1.0 NB A:HEM701 2.0 47.7 1.0 NC A:HEM701 2.0 42.9 1.0 NA A:HEM701 2.0 47.9 1.0 ND A:HEM701 2.0 54.6 1.0 NE2 A:HIS23 2.2 53.4 1.0 SG A:CYS12 2.2 72.9 1.0 C4A A:HEM701 3.0 51.0 1.0 C1B A:HEM701 3.0 49.2 1.0 C1D A:HEM701 3.0 49.2 1.0 C4C A:HEM701 3.1 43.6 1.0 C1A A:HEM701 3.1 49.0 1.0 C4B A:HEM701 3.1 41.5 1.0 C4D A:HEM701 3.1 40.7 1.0 C1C A:HEM701 3.1 43.8 1.0 CD2 A:HIS23 3.1 47.5 1.0 CE1 A:HIS23 3.2 52.7 1.0 CHB A:HEM701 3.4 50.8 1.0 CHD A:HEM701 3.4 42.1 1.0 CHA A:HEM701 3.4 42.4 1.0 CHC A:HEM701 3.4 39.5 1.0 CB A:CYS12 3.4 74.2 1.0 CA A:CYS12 4.1 74.2 1.0 C3A A:HEM701 4.2 54.8 1.0 C2A A:HEM701 4.2 53.0 1.0 C2D A:HEM701 4.3 46.8 1.0 C2B A:HEM701 4.3 48.1 1.0 C3D A:HEM701 4.3 41.1 1.0 C3B A:HEM701 4.3 44.0 1.0 ND1 A:HIS23 4.3 47.3 1.0 C3C A:HEM701 4.3 43.0 1.0 C2C A:HEM701 4.3 43.0 1.0 CG A:HIS23 4.3 42.4 1.0 NH1 A:ARG225 4.7 43.9 1.0 CB A:TRP14 4.8 60.7 1.0 N A:THR13 4.8 69.0 1.0 C A:CYS12 4.9 73.2 1.0

Iron binding site 2 out of 2 in the Structure of Active Cystathionine B-Synthase From Apis Mellifera


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Structure of Active Cystathionine B-Synthase From Apis Mellifera within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe701 b:57.6 occ:1.00 FE B:HEM701 0.0 57.6 1.0 ND B:HEM701 2.0 55.9 1.0 NA B:HEM701 2.0 87.0 1.0 NB B:HEM701 2.0 63.5 1.0 NC B:HEM701 2.0 54.4 1.0 SG B:CYS12 2.2 69.8 1.0 NE2 B:HIS23 2.2 50.4 1.0 C1A B:HEM701 3.0 82.9 1.0 C4A B:HEM701 3.0 84.5 1.0 C4D B:HEM701 3.0 62.9 1.0 CD2 B:HIS23 3.0 49.2 1.0 C1D B:HEM701 3.0 54.5 1.0 C1B B:HEM701 3.1 67.4 1.0 C4C B:HEM701 3.1 51.0 1.0 C1C B:HEM701 3.1 51.6 1.0 C4B B:HEM701 3.1 63.0 1.0 CE1 B:HIS23 3.3 60.7 1.0 CHA B:HEM701 3.4 72.7 1.0 CHB B:HEM701 3.4 75.0 1.0 CHD B:HEM701 3.4 51.2 1.0 CB B:CYS12 3.4 67.0 1.0 CHC B:HEM701 3.4 55.6 1.0 CA B:CYS12 4.0 70.2 1.0 C2A B:HEM701 4.2 84.3 1.0 C3A B:HEM701 4.2 85.8 1.0 CG B:HIS23 4.2 47.9 1.0 C3D B:HEM701 4.2 63.1 1.0 C2D B:HEM701 4.2 56.3 1.0 C2B B:HEM701 4.3 70.4 1.0 C2C B:HEM701 4.3 49.4 1.0 C3C B:HEM701 4.3 49.6 1.0 C3B B:HEM701 4.3 66.9 1.0 ND1 B:HIS23 4.3 48.4 1.0 CB B:TRP14 4.8 58.4 1.0 N B:THR13 4.8 64.3 1.0 C B:CYS12 4.8 67.5 1.0 NH1 B:ARG225 4.9 57.7 1.0 N B:TRP14 5.0 74.3 1.0

P.Gimenez-Mascarell, T.Majtan, I.Oyenarte, J.Ereno-Orbea, J.Majtan, J.Klaudiny, J.P.Kraus, L.A.Martinez-Cruz. Crystal Structure of Cystathionine Beta-Synthase From Honeybee Apis Mellifera. J. Struct. Biol. V. 202 82 2018.
ISSN: ESSN 1095-8657
PubMed: 29275181
DOI: 10.1016/J.JSB.2017.12.008