Iron in PDB 1yzi: A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin

The structure of A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin, PDB code: 1yzi was solved by M.K.Safo, D.J.Abraham, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	58.00 / 2.07
Space group	P 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	61.464, 61.464, 174.750, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 25.7

The binding sites of Iron atom in the A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin (pdb code 1yzi). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin, PDB code: 1yzi:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe143 b:38.9 occ:1.00 FE A:HEM143 0.0 38.9 1.0 C A:CMO142 1.8 27.9 1.0 NE2 A:HIS87 2.0 32.5 1.0 NA A:HEM143 2.0 37.7 1.0 NB A:HEM143 2.0 36.8 1.0 NC A:HEM143 2.0 36.4 1.0 ND A:HEM143 2.1 41.0 1.0 O A:CMO142 2.9 45.4 1.0 CE1 A:HIS87 3.0 32.2 1.0 CD2 A:HIS87 3.0 40.2 1.0 C4B A:HEM143 3.0 33.4 1.0 C1A A:HEM143 3.0 43.5 1.0 C1C A:HEM143 3.0 39.1 1.0 C4D A:HEM143 3.1 44.2 1.0 C4A A:HEM143 3.1 38.4 1.0 C4C A:HEM143 3.1 40.9 1.0 C1D A:HEM143 3.1 44.8 1.0 C1B A:HEM143 3.1 39.5 1.0 CHC A:HEM143 3.3 35.0 1.0 CHA A:HEM143 3.4 36.9 1.0 CHD A:HEM143 3.5 37.6 1.0 CHB A:HEM143 3.5 36.6 1.0 ND1 A:HIS87 4.1 31.4 1.0 CG A:HIS87 4.2 42.7 1.0 C3B A:HEM143 4.3 38.1 1.0 C3A A:HEM143 4.3 34.2 1.0 C3D A:HEM143 4.3 45.3 1.0 C2B A:HEM143 4.3 34.6 1.0 C2C A:HEM143 4.3 37.1 1.0 C2A A:HEM143 4.3 40.7 1.0 C3C A:HEM143 4.3 35.7 1.0 NE2 A:HIS58 4.4 43.8 1.0 C2D A:HEM143 4.4 41.4 1.0 CG2 A:VAL62 4.9 38.2 1.0

Iron binding site 2 out of 2 in the A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe148 b:56.6 occ:1.00 FE B:HEM148 0.0 56.6 1.0 C B:CMO147 1.9 52.2 1.0 NB B:HEM148 2.0 55.0 1.0 NE2 B:HIS92 2.1 55.7 1.0 NC B:HEM148 2.1 51.2 1.0 ND B:HEM148 2.1 55.1 1.0 NA B:HEM148 2.1 56.7 1.0 CE1 B:HIS92 3.0 58.7 1.0 C4B B:HEM148 3.1 53.7 1.0 C1B B:HEM148 3.1 56.5 1.0 O B:CMO147 3.1 56.8 1.0 C1C B:HEM148 3.1 52.9 1.0 C4A B:HEM148 3.1 55.2 1.0 CD2 B:HIS92 3.1 50.6 1.0 C1D B:HEM148 3.1 57.8 1.0 C4D B:HEM148 3.2 57.3 1.0 C1A B:HEM148 3.2 50.9 1.0 C4C B:HEM148 3.2 50.9 1.0 CHC B:HEM148 3.4 53.8 1.0 CHB B:HEM148 3.4 58.5 1.0 CHD B:HEM148 3.5 54.1 1.0 CHA B:HEM148 3.5 53.8 1.0 ND1 B:HIS92 4.2 61.4 1.0 CG B:HIS92 4.3 59.9 1.0 C2B B:HEM148 4.4 56.7 1.0 C3B B:HEM148 4.4 55.7 1.0 C3A B:HEM148 4.4 54.4 1.0 C3D B:HEM148 4.4 60.6 1.0 C2C B:HEM148 4.4 48.6 1.0 C2A B:HEM148 4.4 52.5 1.0 C2D B:HEM148 4.4 60.8 1.0 C3C B:HEM148 4.5 49.6 1.0 CG2 B:VAL67 4.5 59.5 1.0 CE1 B:HIS63 4.6 46.2 1.0

M.K.Safo, D.J.Abraham. The Enigma of the Liganded Hemoglobin End State: A Novel Quaternary Structure of Human Carbonmonoxy Hemoglobin. Biochemistry V. 44 8347 2005.
ISSN: ISSN 0006-2960
PubMed: 15938624
DOI: 10.1021/BI050412Q